ULK1 phosphorylates Sec23A and mediates autophagy-induced inhibition of ER-to-Golgi traffic

Abstract Background Autophagy is an inducible autodigestive process that allows cells to recycle proteins and other materials for survival during stress and nutrient deprived conditions. The kinase ULK1 is required to activate this process. ULK1 phosphorylates a number of target proteins and regulat...

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Bibliographic Details
Main Authors: Wenjia Gan, Caiyun Zhang, Ka Yu Siu, Ayano Satoh, Julian A. Tanner, Sidney Yu
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Cell Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12860-017-0138-8