Reversal of Ovarian Cancer Cell Lines Multidrug Resistance Phenotype by the Association of Apiole with Chemotherapies

Reversal of Ovarian Cancer Cell Lines Multidrug Resistance Phenotype by the Association of Apiole with Chemotherapies

<b> </b>Multidrug resistance (MDR) is the main obstacle in anticancer therapy. The use of drug combinations to circumvent tumor resistance is a well-established principle in the clinic. Among the therapeutic targets, glycoprotein-P (P-gp), an energy-dependent transmembrane efflux pump re...

Full description

Bibliographic Details
Main Authors: Carolina Afonso de Lima, Ian Lucas de Souza Bueno, Stanley Nunes Siqueira Vasconcelos, Juliana Mozer Sciani, Ana Lúcia Tasca Gois Ruiz, Mary Ann Foglio, João Ernesto de Carvalho, Giovanna Barbarini Longato
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceuticals
Subjects:
multidrug resistance
glycoprotein-P
apiole
in silico
druglikeness
Online Access:https://www.mdpi.com/1424-8247/13/10/327

Internet

https://www.mdpi.com/1424-8247/13/10/327

Similar Items