Effect of PEEP and tidal volume on ventilation distribution and end-expiratory lung volume: a prospective experimental animal and pilot clinical study.

<h4>Introduction</h4>Lung-protective ventilation aims at using low tidal volumes (VT) at optimum positive end-expiratory pressures (PEEP). Optimum PEEP should recruit atelectatic lung regions and avoid tidal recruitment and end-inspiratory overinflation. We examined the effect of VT and...

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Bibliographic Details
Main Authors: Günther Zick, Gunnar Elke, Tobias Becher, Dirk Schädler, Sven Pulletz, Sandra Freitag-Wolf, Norbert Weiler, Inéz Frerichs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23991138/pdf/?tool=EBI