The Causes and Consequences of Spatial Organization of the Genome in Regulation of Gene Expression

Regulation of gene expression in time, space and quantity is orchestrated by the functional interplay of cis-acting elements and trans-acting factors. Our current view postulates that transcription factors recognize enhancer DNA and read the transcriptional regulatory code by cooperative DNA binding...

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Bibliographic Details
Main Authors: Marios Agelopoulos, Spyros Foutadakis, Dimitris Thanos
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.682397/full