Prion Variants of Yeast are Numerous, Mutable, and Segregate on Growth, Affecting Prion Pathogenesis, Transmission Barriers, and Sensitivity to Anti-Prion Systems

The known amyloid-based prions of Saccharomyces cerevisiae each have multiple heritable forms, called “prion variants” or “prion strains”. These variants, all based on the same prion protein sequence, differ in their biological properties and their detailed am...

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Bibliographic Details
Main Authors: Reed B. Wickner, Moonil Son, Herman K. Edskes
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/11/3/238