Reactivation of Latent HIV-1 by Inhibition of BRD4

Reactivation of Latent HIV-1 by Inhibition of BRD4

HIV-1 depends on many host factors for propagation. Other host factors, however, antagonize HIV-1 and may have profound effects on viral activation. Curing HIV-1 requires the reduction of latent viral reservoirs that remain in the face of antiretroviral therapy. Using orthologous genetic screens, w...

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Bibliographic Details
Main Authors: Jian Zhu, Gaurav D. Gaiha, Sinu P. John, Thomas Pertel, Christopher R. Chin, Geng Gao, Hongjing Qu, Bruce D. Walker, Stephen J. Elledge, Abraham L. Brass
Format: Article
Language:English
Published: Elsevier 2012-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712002896

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http://www.sciencedirect.com/science/article/pii/S2211124712002896

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