De novo assembly of the complex genome of Nippostrongylus brasiliensis using MinION long reads

De novo assembly of the complex genome of Nippostrongylus brasiliensis using MinION long reads

Abstract Background Eukaryotic genome assembly remains a challenge in part due to the prevalence of complex DNA repeats. This is a particularly acute problem for holocentric nematodes because of the large number of satellite DNA sequences found throughout their genomes. These have been recalcitrant...

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Bibliographic Details
Main Authors: David Eccles, Jodie Chandler, Mali Camberis, Bernard Henrissat, Sergey Koren, Graham Le Gros, Jonathan J. Ewbank
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Biology
Subjects:
Helminths
Next-generation sequencing
Base-calling
Genome assembly
DNA repeat
Population analysis
Online Access:http://link.springer.com/article/10.1186/s12915-017-0473-4

Internet

http://link.springer.com/article/10.1186/s12915-017-0473-4

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