Pharmacokinetic study of eplerenone in rats after long-term coadministration with buckwheat tea

Pharmacokinetic study of eplerenone in rats after long-term coadministration with buckwheat tea

The aim of this study was to investigate the effect of long-term intake of Tartary buckwheat tea on the pharmacokinetics (PK) of eplerenone in rats. A validated high-performance liquid chromatography-mass spectrometry (HPLC-MS) method was established to determine the eplerenone in plasma, and the po...

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Bibliographic Details
Main Authors: Liang Zou, Kun Jia, Rui Li, Ping Wang, Jun-Zhi Lin, Hui-Juan Chen, Gang Zhao, Lian-Xin Peng
Format: Article
Language:English
Published: Wiley 2016-04-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Coadministration
Eplerenone
Hypertension
Pharmacokinetics
Tartary buckwheat
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X1630002X

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http://www.sciencedirect.com/science/article/pii/S1607551X1630002X

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