Single molecule and multiple bond characterization of catch bond associated cytoadhesion in malaria

Abstract The adhesion of malaria infected red blood cells (iRBCs) to host endothelial receptors in the microvasculature, or cytoadhesion, is associated with severe disease pathology such as multiple organ failure and cerebral malaria. Malaria iRBCs have been shown to bind to several receptors, of wh...

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Bibliographic Details
Main Authors: Ying Bena Lim, Juzar Thingna, Jianshu Cao, Chwee Teck Lim
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04352-x