In Vitro Manganese Exposure Disrupts MAPK Signaling Pathways in Striatal and Hippocampal Slices from Immature Rats

In Vitro Manganese Exposure Disrupts MAPK Signaling Pathways in Striatal and Hippocampal Slices from Immature Rats

The molecular mechanisms mediating manganese (Mn)-induced neurotoxicity, particularly in the immature central nervous system, have yet to be completely understood. In this study, we investigated whether mitogen-activated protein kinases (MAPKs) and tyrosine hydroxylase (TH) could represent potential...

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Bibliographic Details
Main Authors: Tanara Vieira Peres, Daniela Zótico Pedro, Fabiano Mendes de Cordova, Mark William Lopes, Filipe Marques Gonçalves, Cláudia Beatriz Nedel Mendes-de-Aguiar, Roger Walz, Marcelo Farina, Michael Aschner, Rodrigo Bainy Leal
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/769295

Internet

http://dx.doi.org/10.1155/2013/769295

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