DNA Damage Tolerance Mechanisms Revealed from the Analysis of <i>Immunoglobulin V</i> Gene Diversification in Avian DT40 Cells
DNA replication is an essential biochemical reaction in dividing cells that frequently stalls at damaged sites. Homologous/homeologous recombination (HR)-mediated template switch and translesion DNA synthesis (TLS)-mediated bypass processes release arrested DNA replication forks. These mechanisms ar...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-12-01
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Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/9/12/614 |