Regulation of the Inflammasome by Ceramide in Cystic Fibrosis Lungs

Background: Cystic fibrosis (CF), the most common autosomal recessive disorder in Western countries, is characterized by chronic pulmonary inflammation, reduced mucociliary clearance, and increased susceptibility to infection. Our studies using Cftr-deficient mice and human CF specimens showed that...

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Bibliographic Details
Main Authors: Heike Grassmé, Alexander Carpinteiro, Michael J. Edwards, Erich Gulbins, Katrin Anne Becker
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/362983