Regulation of the Inflammasome by Ceramide in Cystic Fibrosis Lungs
Background: Cystic fibrosis (CF), the most common autosomal recessive disorder in Western countries, is characterized by chronic pulmonary inflammation, reduced mucociliary clearance, and increased susceptibility to infection. Our studies using Cftr-deficient mice and human CF specimens showed that...
Main Authors: | Heike Grassmé, Alexander Carpinteiro, Michael J. Edwards, Erich Gulbins, Katrin Anne Becker |
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Format: | Article |
Language: | English |
Published: |
Cell Physiol Biochem Press GmbH & Co KG
2014-06-01
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Series: | Cellular Physiology and Biochemistry |
Subjects: | |
Online Access: | http://www.karger.com/Article/FullText/362983 |
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