In situ Immune Signatures and Microbial Load at the Nasopharyngeal Interface in Children With Acute Respiratory Infection

In situ Immune Signatures and Microbial Load at the Nasopharyngeal Interface in Children With Acute Respiratory Infection

Acute respiratory infection (ARI) is the most frequent cause for hospitalization in infants and young children. Using multiplexed nCounter technology to digitally quantify 600 human mRNAs in parallel with 14 virus- and 5 bacterium-specific RNAs, we characterized viral and bacterial presence in nasop...

Full description

Bibliographic Details
Main Authors: Kiyoshi F. Fukutani, Cristiana M. Nascimento-Carvalho, Maiara L. Bouzas, Juliana R. Oliveira, Aldina Barral, Tim Dierckx, Ricardo Khouri, Helder I. Nakaya, Bruno B. Andrade, Johan Van Weyenbergh, Camila I. de Oliveira
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Microbiology
Subjects:
network analysis
ARI
immune response
nCounter
interferon
viral load
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02475/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.02475/full

Similar Items