Brain structural correlates of insomnia severity in 1053 individuals with major depressive disorder: results from the ENIGMA MDD Working Group

Abstract It has been difficult to find robust brain structural correlates of the overall severity of major depressive disorder (MDD). We hypothesized that specific symptoms may better reveal correlates and investigated this for the severity of insomnia, both a key symptom and a modifiable major risk...

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Main Authors: Jeanne Leerssen, Tessa F. Blanken, Elena Pozzi, Neda Jahanshad, Lyubomir Aftanas, Ole A. Andreassen, Bernhard T. Baune, Ivan Brack, Angela Carballedo, Christopher R. K. Ching, Udo Dannlowski, Katharina Dohm, Verena Enneking, Elena Filimonova, Stella M. Fingas, Thomas Frodl, Beata R. Godlewska, Janik Goltermann, Ian H. Gotlib, Dominik Grotegerd, Oliver Gruber, Mathew A. Harris, Sean N. Hatton, Emma Hawkins, Ian B. Hickie, Natalia Jaworska, Tilo Kircher, Axel Krug, Jim Lagopoulos, Hannah Lemke, Meng Li, Frank P. MacMaster, Andrew M. McIntosh, Quinn McLellan, Susanne Meinert, Benson Mwangi, Igor Nenadić, Evgeny Osipov, Maria J. Portella, Ronny Redlich, Jonathan Repple, Matthew D. Sacchet, Philipp G. Sämann, Egle Simulionyte, Jair C. Soares, Martin Walter, Norio Watanabe, Heather C. Whalley, Dilara Yüksel, Dick J. Veltman, Paul M. Thompson, Lianne Schmaal, Eus J. W. Van Someren
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-020-01109-5