The flagellum of Pseudomonas aeruginosa is required for resistance to clearance by surfactant protein A.
Surfactant protein A (SP-A) is an important lung innate immune protein that kills microbial pathogens by opsonization and membrane permeabilization. We investigated the basis of SP-A-mediated pulmonary clearance of Pseudomonas aeruginosa using genetically-engineered SP-A mice and a library of signat...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-06-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC1891440?pdf=render |