The within-host fitness of HIV-1 increases with age in ART-naïve HIV-1 subtype C infected children

Abstract As the immune system develops with age, children combat infections better. HIV-1, however, targets an activated immune system, potentially rendering children increasingly permissive to HIV-1 infection as they grow. How HIV-1 fitness changes with age in children is unknown. Here, we estimate...

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Bibliographic Details
Main Authors: Pradeep Nagaraja, Bindu P. Gopalan, Reena R. D’Souza, Debolina Sarkar, Niharika Rajnala, Narendra M. Dixit, Anita Shet
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82293-2