Understanding the Virulence of Staphylococcus pseudintermedius: A Major Role of Pore-Forming Toxins

Understanding the Virulence of Staphylococcus pseudintermedius: A Major Role of Pore-Forming Toxins

Staphylococcus pseudintermedius is responsible for severe and necrotizing infections in humans and dogs. Contrary to S. aureus, the pathophysiological mechanisms involved in this virulence are incompletely understood. We previously showed the intracellular cytotoxicity induced after internalization...

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Bibliographic Details
Main Authors: Yousef Maali, Cédric Badiou, Patrícia Martins-Simões, Elisabeth Hodille, Michele Bes, François Vandenesch, Gérard Lina, Alan Diot, Frederic Laurent, Sophie Trouillet-Assant
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Staphylococcus pseudintermedius
pore-forming toxins
phenol-soluble modulins
leukotoxin Luk-I
CXCR2 receptor
cytotoxicity
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00221/full

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https://www.frontiersin.org/article/10.3389/fcimb.2018.00221/full

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