A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior.

A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior.

Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays to detect copy number variants (CNV) among inbred mouse strains and thereby identified a approximately 475 kb tandem duplication on chromosome...

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Bibliographic Details
Main Authors: Richard Williams, Jackie E Lim, Bettina Harr, Claudia Wing, Ryan Walters, Margaret G Distler, Meike Teschke, Chunlei Wu, Tim Wiltshire, Andrew I Su, Greta Sokoloff, Lisa M Tarantino, Justin O Borevitz, Abraham A Palmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2650792?pdf=render

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http://europepmc.org/articles/PMC2650792?pdf=render

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