Telomere Length in Chromosomally Normal and Abnormal Miscarriages and Ongoing Pregnancies and Its Association with 5-hydroxymethylcytosine Patterns

Telomere Length in Chromosomally Normal and Abnormal Miscarriages and Ongoing Pregnancies and Its Association with 5-hydroxymethylcytosine Patterns

The present study investigates telomere length (TL) in dividing chorionic cytotrophoblast cells from karyotypically normal and abnormal first trimester miscarriages and ongoing pregnancies. Using Q-FISH, we measured relative TLs in the metaphase chromosomes of 61 chorionic villous samples. Relative...

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Bibliographic Details
Main Authors: Mikhail I. Krapivin, Andrei V. Tikhonov, Olga A. Efimova, Anna A. Pendina, Anna A. Smirnova, Olga G. Chiryaeva, Olga E. Talantova, Lubov’ I. Petrova, Vera S. Dudkina, Vladislav S. Baranov
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
telomeres
chorionic cytotrophoblast
pregnancy
miscarriage
telomere length
5-hydroxymethylcytosine
Online Access:https://www.mdpi.com/1422-0067/22/12/6622

Internet

https://www.mdpi.com/1422-0067/22/12/6622

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