Combination of Heme Oxygenase-1 Inhibition and Sigma Receptor Modulation for Anticancer Activity

Combination of Heme Oxygenase-1 Inhibition and Sigma Receptor Modulation for Anticancer Activity

Cancer is a multifactorial disease that may be tackled by targeting different signaling pathways. Heme oxygenase-1 (HO-1) and sigma receptors (σRs) are both overexpressed in different human cancers, including prostate and brain, contributing to the cancer spreading. In the present study, we investig...

Full description

Bibliographic Details
Main Authors: Giuseppe Romeo, Valeria Ciaffaglione, Emanuele Amata, Maria Dichiara, Loredana Calabrese, Luca Vanella, Valeria Sorrenti, Salvo Grosso, Agata Grazia D’Amico, Velia D’Agata, Sebastiano Intagliata, Loredana Salerno
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
heme oxygenase
HO-1 inhibitors
sigma receptors
σR ligands
DU145
anticancer activity
Online Access:https://www.mdpi.com/1420-3049/26/13/3860

Internet

https://www.mdpi.com/1420-3049/26/13/3860

Similar Items