Coevolution trumps pleiotropy: carbon assimilation traits are independent of metabolic network structure in budding yeast.

Phenotypic traits may be gained and lost together because of pleiotropy, the involvement of common genes and networks, or because of simultaneous selection for multiple traits across environments (multiple-trait coevolution). However, the extent to which network pleiotropy versus environmental coevo...

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Bibliographic Details
Main Authors: Dana A Opulente, Christopher M Morales, Lucas B Carey, Joshua S Rest
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3542375?pdf=render