In Silico SAR Studies of HIV-1 Inhibitors

In Silico SAR Studies of HIV-1 Inhibitors

Quantitative Structure Activity Relationships (QSAR or SAR) have helped scientists to establish mathematical relationships between molecular structures and their biological activities. In the present article, SAR studies have been carried out on 89 tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepine (TIB...

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Bibliographic Details
Main Authors: Ismail Hdoufane, Imane Bjij, Mahmoud Soliman, Alia Tadjer, Didier Villemin, Jane Bogdanov, Driss Cherqaoui
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Pharmaceuticals
Subjects:
structure activity relationship
TIBO
HIV inhibitors
support vector machines
decision trees
random forests and artificial neural networks
Online Access:http://www.mdpi.com/1424-8247/11/3/69

Internet

http://www.mdpi.com/1424-8247/11/3/69

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