The new SARS-CoV-2 strain shows a stronger binding affinity to ACE2 due to N501Y mutant

SARS-CoV-2 is a global challenge due to its ability to spread much faster than the SARS-CoV, which was attributed to the mutations in the receptor binding domain (RBD). These mutations enhanced the electrostatic interactions. Recently, a new strain is reported in the UK that includes a mutation (N50...

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Bibliographic Details
Main Authors: Fedaa Ali, Amal Kasry, Muhamed Amin
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Medicine in Drug Discovery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590098621000075