Long term metabolic syndrome induced by a high fat high fructose diet leads to minimal renal injury in C57BL/6 mice.

Long term metabolic syndrome induced by a high fat high fructose diet leads to minimal renal injury in C57BL/6 mice.

Metabolic syndrome can induce chronic kidney disease in humans. Genetically engineered mice on a C57BL/6 background are highly used for mechanistic studies. Although it has been shown that metabolic syndrome induces cardiovascular lesions in C57BL/6 mice, in depth renal phenotyping has never been pe...

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Bibliographic Details
Main Authors: Romain Dissard, Julie Klein, Cécile Caubet, Benjamin Breuil, Justyna Siwy, Janosch Hoffman, Laurent Sicard, Laure Ducassé, Simon Rascalou, Bruno Payre, Marie Buléon, William Mullen, Harald Mischak, Ivan Tack, Jean-Loup Bascands, Bénédicte Buffin-Meyer, Joost P Schanstra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3789664?pdf=render

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http://europepmc.org/articles/PMC3789664?pdf=render

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