Long term metabolic syndrome induced by a high fat high fructose diet leads to minimal renal injury in C57BL/6 mice.
Metabolic syndrome can induce chronic kidney disease in humans. Genetically engineered mice on a C57BL/6 background are highly used for mechanistic studies. Although it has been shown that metabolic syndrome induces cardiovascular lesions in C57BL/6 mice, in depth renal phenotyping has never been pe...
Main Authors: | Romain Dissard, Julie Klein, Cécile Caubet, Benjamin Breuil, Justyna Siwy, Janosch Hoffman, Laurent Sicard, Laure Ducassé, Simon Rascalou, Bruno Payre, Marie Buléon, William Mullen, Harald Mischak, Ivan Tack, Jean-Loup Bascands, Bénédicte Buffin-Meyer, Joost P Schanstra |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3789664?pdf=render |
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