Antibody-dependent transplacental transfer of malaria blood-stage antigen using a human ex vivo placental perfusion model.

Prenatal exposure to allergens or antigens released by infections during pregnancy can stimulate an immune response or induce immunoregulatory networks in the fetus affecting susceptibility to infection and disease later in life. How antigen crosses from the maternal to fetal environment is poorly u...

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Bibliographic Details
Main Authors: Karen May, Markus Grube, Indu Malhotra, Carole A Long, Sanjay Singh, Kishor Mandaliya, Werner Siegmund, Christoph Fusch, Henning Schneider, Christopher L King
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2777305?pdf=render