Heparan Sulfate as a Therapeutic Target in Tauopathies: Insights From Zebrafish

Microtubule-associated protein tau (MAPT) hyperphosphorylation and aggregation, are two hallmarks of a family of neurodegenerative disorders collectively referred to as tauopathies. In many tauopathies, including Alzheimer’s disease (AD), progressive supranuclear palsy (PSP) and Pick’s disease, tau...

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Bibliographic Details
Main Authors: Seyedeh Maryam Alavi Naini, Nadia Soussi-Yanicostas
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
tau
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2018.00163/full