IL-3 and CSF-1 interact to promote generation of CD11c+ IL-10-producing macrophages.

Unraveling the mechanisms of hematopoiesis regulated by multiple cytokines remains a challenge in hematology. IL-3 is an allergic cytokine with the multilineage potential, while CSF-1 is produced in the steady state with restricted lineage coverage. Here, we uncovered an instructive role of CSF-1 in...

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Bibliographic Details
Main Authors: Kuo-Ching Sheng, Lara J Herrero, Adam Taylor, Andrew J Hapel, Suresh Mahalingam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3990611?pdf=render