Divergent Small Tim Homologues Are Associated with TbTim17 and Critical for the Biogenesis of TbTim17 Protein Complexes in Trypanosoma brucei

Divergent Small Tim Homologues Are Associated with TbTim17 and Critical for the Biogenesis of TbTim17 Protein Complexes in Trypanosoma brucei

Trypanosoma brucei is the causative agent of African sleeping sickness. The parasite’s mitochondrion represents a useful source for potential chemotherapeutic targets. Similarly to yeast and humans, mitochondrial functions depend on the import of proteins that are encoded in the nucleus and made in...

Full description

Bibliographic Details
Main Authors: Joseph T. Smith, Ujjal K. Singha, Smita Misra, Minu Chaudhuri
Format: Article
Language:English
Published: American Society for Microbiology 2018-06-01
Series:mSphere
Subjects:
TbTim17
Trypanosoma brucei
mitochondria
protein import
small Tims
Online Access:https://doi.org/10.1128/mSphere.00204-18

Internet

https://doi.org/10.1128/mSphere.00204-18

Similar Items