Boosting probabilistic graphical model inference by incorporating prior knowledge from multiple sources.

Inferring regulatory networks from experimental data via probabilistic graphical models is a popular framework to gain insights into biological systems. However, the inherent noise in experimental data coupled with a limited sample size reduces the performance of network reverse engineering. Prior k...

Full description

Bibliographic Details
Main Authors: Paurush Praveen, Holger Fröhlich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3691143?pdf=render