Model-based therapeutic correction of hypothalamic-pituitary-adrenal axis dysfunction.
The hypothalamic-pituitary-adrenal (HPA) axis is a major system maintaining body homeostasis by regulating the neuroendocrine and sympathetic nervous systems as well modulating immune function. Recent work has shown that the complex dynamics of this system accommodate several stable steady states, o...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-01-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2613527?pdf=render |