L-arginine supplementation reduces mortality and improves disease outcome in mice infected with Trypanosoma cruzi.

Chagas disease caused by Trypanosoma cruzi is a neglected disease that affects about 7 million people in Latin America, recently emerging on other continents due to migration. As infection in mice is characterized by depletion of plasma L-arginine, the effect on infection outcome was tested in mice...

Full description

Bibliographic Details
Main Authors: Sofía Carbajosa, Héctor O Rodríguez-Angulo, Susana Gea, Carlos Chillón-Marinas, Cristina Poveda, María C Maza, Diana Colombet, Manuel Fresno, Núria Gironès
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5786330?pdf=render