Study on synergistic effect of Rac1 inhibitor and temozolomide in inhibiting proliferation and invasiveness of glioma cells in vitro

Study on synergistic effect of Rac1 inhibitor and temozolomide in inhibiting proliferation and invasiveness of glioma cells in vitro

<p><strong>Objective </strong> To investigate whether Rac1 inhibitor has a synergistic effect on temozolomide (TMZ) in inhibiting the proliferation, migration and invasiveness of glioma cells.  <strong>Methods</strong> Human glioma cell lines U87 and U251 were cultur...

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Bibliographic Details
Main Authors: Xiao-yong HAN, Xi-rui WANG, Zhi-huang ZHAO, Jin-xing SHANG, Gang-feng YIN, Xue-jun YANG
Format: Article
Language:English
Published: Tianjin Huanhu Hospital 2016-08-01
Series:Chinese Journal of Contemporary Neurology and Neurosurgery
Subjects:
Glioma
rac1 GTP-binding protein
Temozolomide (not in MeSH)
Cell proliferation
Neoplasm invasiveness
Tumor cells, cultured
Online Access:http://www.cjcnn.org/index.php/cjcnn/article/view/1444

Internet

http://www.cjcnn.org/index.php/cjcnn/article/view/1444

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