Age-Dependent Changes of Adipokine and Cytokine Secretion From Rat Adipose Tissue by Endogenous and Exogenous Toll-Like Receptor Agonists

Age-Dependent Changes of Adipokine and Cytokine Secretion From Rat Adipose Tissue by Endogenous and Exogenous Toll-Like Receptor Agonists

White adipose tissue but recently also brown adipose tissue have emerged as endocrine organs. Age-associated obesity is accompanied by prolonged and elevated lipopolysaccharide (LPS)-induced sickness symptoms and increased cytokine and adipokine levels in the circulation partially originating from a...

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Bibliographic Details
Main Authors: Verena Peek, Elena Neumann, Tomohiro Inoue, Sandy Koenig, Fabian Johannes Pflieger, Rüdiger Gerstberger, Joachim Roth, Kiyoshi Matsumura, Christoph Rummel
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
adipokines
cytokines
batokines
lipopolysaccharide
high mobility group box-1 protein
biglycan
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01800/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01800/full

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