Regulation of Ca2+/Calmodulin-Dependent Protein Kinase II Signaling within Hippocampal Glutamatergic Postsynapses during Flurazepam Withdrawal

Cessation of one-week oral administration of the benzodiazepine flurazepam (FZP) to rats results in withdrawal anxiety after 1 day of withdrawal. FZP withdrawal is correlated with synaptic incorporation of homomeric GluA1-containing α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors (AMP...

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Bibliographic Details
Main Authors: Damien E. Earl, Paromita Das, William T. Gunning, Elizabeth I. Tietz
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2012/405926