Pathogenic missense mutation pattern of forkhead box genes in neurodevelopmental disorders

Pathogenic missense mutation pattern of forkhead box genes in neurodevelopmental disorders

Abstract Background Forkhead box (FOX) proteins are a family of transcription factors. Mutations of three FOX genes, including FOXP1, FOXP2, and FOXG1, have been reported in neurodevelopmental disorders (NDDs). However, due to the lack of site‐specific statistical significance, the pathogenicity of...

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Bibliographic Details
Main Authors: Lin Han, Meilin Chen, Yazhe Wang, Huidan Wu, Yingting Quan, Ting Bai, Kuokuo Li, Guiqin Duan, Yan Gao, Zhengmao Hu, Kun Xia, Hui Guo
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
de novo
forkhead box domain
FOXG1
FOXP1
FOXP2
missense variant
Online Access:https://doi.org/10.1002/mgg3.789

Internet

https://doi.org/10.1002/mgg3.789

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