Quorum sensing negatively regulates multinucleate cell formation during intracellular growth of Burkholderia pseudomallei in macrophage-like cells.

Quorum sensing negatively regulates multinucleate cell formation during intracellular growth of Burkholderia pseudomallei in macrophage-like cells.

Burkholderia pseudomallei is a Gram-negative environmental bacterium and the causative agent of melioidosis, a potentially fatal, acute or chronic disease endemic in the tropics. Acyl homoserine lactone (AHL)-mediated quorum sensing and signalling have been associated with virulence and biofilm form...

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Bibliographic Details
Main Authors: Rachel E Horton, Gary D Grant, Ben Matthews, Michael Batzloff, Suzzanne J Owen, Stephanie Kyan, Cameron P Flegg, Amanda M Clark, Glen C Ulett, Nigel Morrison, Ian R Peak, Ifor R Beacham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3660431?pdf=render

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http://europepmc.org/articles/PMC3660431?pdf=render

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