Shootin1a-mediated actin-adhesion coupling generates force to trigger structural plasticity of dendritic spines

Shootin1a-mediated actin-adhesion coupling generates force to trigger structural plasticity of dendritic spines

Summary: Dendritic spines constitute the major compartments of excitatory post-synapses. They undergo activity-dependent enlargement, which is thought to increase the synaptic efficacy underlying learning and memory. The activity-dependent spine enlargement requires activation of signaling pathways...

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Bibliographic Details
Main Authors: Ria Fajarwati Kastian, Takunori Minegishi, Kentarou Baba, Takeo Saneyoshi, Hiroko Katsuno-Kambe, Singh Saranpal, Yasunori Hayashi, Naoyuki Inagaki
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Cell Reports
Subjects:
dendritic spine
synaptic plasticity
actin filaments
shootin1
N-cadherin
L1-CAM
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721004691

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http://www.sciencedirect.com/science/article/pii/S2211124721004691

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