Antigenic differences between AS03 adjuvanted influenza A (H1N1) pandemic vaccines: implications for pandemrix-associated narcolepsy risk.

Antigenic differences between AS03 adjuvanted influenza A (H1N1) pandemic vaccines: implications for pandemrix-associated narcolepsy risk.

<h4>Background</h4>Narcolepsy results from immune-mediated destruction of hypocretin secreting neurons in hypothalamus, however the triggers and disease mechanisms are poorly understood. Vaccine-attributable risk of narcolepsy reported so far with the AS03 adjuvanted H1N1 vaccination Pan...

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Bibliographic Details
Main Authors: Outi Vaarala, Arja Vuorela, Markku Partinen, Marc Baumann, Tobias L Freitag, Seppo Meri, Päivi Saavalainen, Matti Jauhiainen, Rabah Soliymani, Turkka Kirjavainen, Päivi Olsen, Outi Saarenpää-Heikkilä, Juha Rouvinen, Merja Roivainen, Hanna Nohynek, Jukka Jokinen, Ilkka Julkunen, Terhi Kilpi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0114361

Internet

https://doi.org/10.1371/journal.pone.0114361

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