Axl tyrosine kinase protects against tubulo-interstitial apoptosis and progression of renal failure in a murine model of chronic kidney disease and hyperphosphataemia.

Chronic kidney disease (CKD) is defined as the progressive loss of renal function often involving glomerular, tubulo-interstitial and vascular pathology. CKD is associated with vascular calcification; the extent of which predicts morbidity and mortality. However, the molecular regulation of these ev...

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Bibliographic Details
Main Authors: Gareth D Hyde, Rebecca F Taylor, Nick Ashton, Samantha J Borland, Hon Sing Geoffrey Wu, Andrew P Gilmore, Ann E Canfield
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4096921?pdf=render