The growth inhibitory effect of human gingiva-derived mesenchymal stromal cells expressing interferon-β on tongue squamous cell carcinoma cells and xenograft model

The growth inhibitory effect of human gingiva-derived mesenchymal stromal cells expressing interferon-β on tongue squamous cell carcinoma cells and xenograft model

Abstract Background Interferon-β (IFN-β) is a cytokine with pleiotropic cellular functions, including antiviral, antiproliferative, and immunomodulatory activities. IFN-β inhibits multiple tumor cell growth in vitro. However, the contradiction between the therapeutic dose of IFN-β and its maximally...

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Bibliographic Details
Main Authors: Lingqian Du, Qianyu Liang, Shaohua Ge, Chengzhe Yang, Pishan Yang
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Stem Cell Research & Therapy
Subjects:
Gingiva-derived mesenchymal stromal cell
Interferon-β
Tongue squamous cell carcinoma
Proliferation
Online Access:http://link.springer.com/article/10.1186/s13287-019-1320-z

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http://link.springer.com/article/10.1186/s13287-019-1320-z

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