Multiplex Identification of Human Papillomavirus 16 DNA Integration Sites in Cervical Carcinomas.

Cervical cancer is caused by high-risk human papillomaviruses (HPV), in more than half of the worldwide cases by HPV16. Viral DNA integration into the host genome is a frequent mutation in cervical carcinogenesis. Because integration occurs into different genomic locations, it creates unique viral-c...

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Bibliographic Details
Main Authors: Bo Xu, Sasithorn Chotewutmontri, Stephan Wolf, Ursula Klos, Martina Schmitz, Matthias Dürst, Elisabeth Schwarz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3688939?pdf=render