Prediction using step-wise L1, L2 regularization and feature selection for small data sets with large number of features

<p>Abstract</p> <p>Background</p> <p>Machine learning methods are nowadays used for many biological prediction problems involving drugs, ligands or polypeptide segments of a protein. In order to build a prediction model a so called training data set of molecules with me...

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Bibliographic Details
Main Authors: Akutsu Tatsuya, Kamada Mayumi, Demir-Kavuk Ozgur, Knapp Ernst-Walter
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/412