The tyrphostin agent AG490 prevents and reverses type 1 diabetes in NOD mice.

The tyrphostin agent AG490 prevents and reverses type 1 diabetes in NOD mice.

Recent studies in the NOD (non-obese diabetic) mouse model of type 1 diabetes (T1D) support the notion that tyrosine kinase inhibitors have the potential for modulating disease development. However, the therapeutic effects of AG490 on the development of T1D are unknown.Female NOD mice were treated w...

Full description

Bibliographic Details
Main Authors: Abdoreza Davoodi-Semiromi, Clive H Wasserfall, Chang Qing Xia, Rhonda M Cooper-DeHoff, Martin Wabitsch, Michael Clare-Salzler, Mark Atkinson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3351395?pdf=render

Internet

http://europepmc.org/articles/PMC3351395?pdf=render

Similar Items