Abnormal Ribosome Biogenesis Partly Induced p53-Dependent Aortic Medial Smooth Muscle Cell Apoptosis and Oxidative Stress

Ribosome biogenesis is a crucial biological process related to cell proliferation, redox balance, and muscle contractility. Aortic smooth muscle cells (ASMCs) show inhibition of proliferation and apoptosis, along with high levels of oxidative stress in aortic dissection (AD). Theoretically, ribosome...

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Bibliographic Details
Main Authors: Qi Wu, Junmou Hong, Zhiwei Wang, Junxia Hu, Ruoshi Chen, Zhipeng Hu, Bowen Li, Xiaoping Hu, Zhengpei Zhang, Yongle Ruan
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/7064319