Natural cytotoxicity receptors: broader expression patterns and functions in innate and adaptive immune cells

Natural Cytotoxicity Receptors (NCRs) have been classically defined as activating receptors delivering potent signals to Natural Killer (NK) cells in order to lyse harmful cells and to produce inflammatory cytokines. Indeed, the elicitation of NK cell effector-functions after engagement of NCRs with...

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Bibliographic Details
Main Authors: Kelly eHudspeth, Bruno eSilva-Santos, Domenico eMavilio
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00069/full