The significance of interferon-γ in HIV-1 pathogenesis, therapy, and prophylaxis

Interferon-γ (IFNγ) plays various roles in the pathogenesis of HIV/AIDS. In an HIV-1 infected individual, the production of IFNγ is detected as early as the acute phase and continually detected throughout the course of infection. Initially produced to clear the primary infection, IFNγ together wit...

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Bibliographic Details
Main Authors: Shannon Ruth Roff, Ezra Noon Song, Janet Kazuko Yamamoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00498/full