EFFECT OF EDEM1 OVEREXPRESSION ON THE GENERATION AND ASSEMBLY OF MAJOR HISTOCOMPATIBILITY COMPLEXES

Background. A better understanding of the role of endoplasmic reticulum degradation-enhancing alpha-mannosidase – like protein 1 (EDEM1) in endoplasmic reticulum associated degradation (ERAD) may open new therapeutic approaches in autoimmune diseases. Aim. To study ERAD and EDEM1 in the generation...

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Bibliographic Details
Main Authors: Alexandra Circiumaru, Gabriela Chiritoiu, Livia Sima, Mihai Bojinca, Stefana Petrescu
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2016-12-01
Series:Romanian Journal of Rheumatology
Subjects:
Online Access:https://rjr.com.ro/articles/2016.4/RJR_2016_4_Art-02.pdf