EFFECT OF EDEM1 OVEREXPRESSION ON THE GENERATION AND ASSEMBLY OF MAJOR HISTOCOMPATIBILITY COMPLEXES

EFFECT OF EDEM1 OVEREXPRESSION ON THE GENERATION AND ASSEMBLY OF MAJOR HISTOCOMPATIBILITY COMPLEXES

Background. A better understanding of the role of endoplasmic reticulum degradation-enhancing alpha-mannosidase – like protein 1 (EDEM1) in endoplasmic reticulum associated degradation (ERAD) may open new therapeutic approaches in autoimmune diseases. Aim. To study ERAD and EDEM1 in the generation...

Full description

Bibliographic Details
Main Authors:	Alexandra Circiumaru, Gabriela Chiritoiu, Livia Sima, Mihai Bojinca, Stefana Petrescu
Format:	Article
Language:	English
Published:	Amaltea Medical Publishing House 2016-12-01
Series:	Romanian Journal of Rheumatology
Subjects:	endoplasmic reticulum associated degradation edem1 mhc i
Online Access:	https://rjr.com.ro/articles/2016.4/RJR_2016_4_Art-02.pdf

Similar Items

EDEM3 Domains Cooperate to Perform Its Overall Cell Functioning
by: Georgiana Manica, et al.
Published: (2021-02-01)

EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired
by: Marioara Chiritoiu, et al.
Published: (2020-05-01)

Implication du chaperome de la protéine F508del-CFTR dans son transport intracellulaire et/ou sa dégradation : rôle des lectines EDEMs et la mannosidase du RE
by: Sidelarbi, Khadidja
Published: (2017)

EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD
by: GINTO, GEORGE
Published: (2020)

EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD
by: Ginto George, et al.
Published: (2020-02-01)

Study Horizontal Screw Conveyors Efficiency Flat Bottomed Bins EDEM Simulation
by: Yanping YAO, et al.
Published: (2013-11-01)

Comparison of Cohesive Models in EDEM and LIGGGHTS for Simulating Powder Compaction
by: Cristina Ramírez-Aragón, et al.
Published: (2018-11-01)

Granular Stack Density’s Influence on Homogeneous Fluidization Regime: Numerical Study Based on EDEM-CFD Coupling
by: Aboubacar Sidiki Drame, et al.
Published: (2021-09-01)

[en] THE ROLE OF MEMORY IN THE (RE)CONSTRUCTION OF ORGANIZATIONAL IDENTITY: THE CASE OF EDEM SCHOOL
by: ALICE FUCS
Published: (2019)

Study on Wear Properties of the Flow Parts in a Centrifugal Pump Based on EDEM–Fluent Coupling
by: Si Huang, et al.
Published: (2019-07-01)

EDEM Investigation and Experimental Evaluation of Abrasive Wear Resistance Performance of Bionic Micro-Thorn and Convex Hull Geometrically Coupled Structured Surface
by: Qingzhu Zhang, et al.
Published: (2021-07-01)

Major Histocompatibility Complex
by: Ozlem Goruroglu Ozturk
Published: (2011-06-01)

The major histocompatibility complex of reindeer
by: I. Olsaker, et al.
Published: (1990-09-01)

Characterisation of SHERP, a novel protein expressed in infective stages of Leishmania major
by: Knuepfer, Ellen
Published: (2001)

Amino acid sequences within the β1 domain of human apolipoprotein B can mediate rapid intracellular degradation
by: Louis R. Lapierre, et al.
Published: (2004-02-01)

lncRNA Xist regulates sevoflurane-induced social and emotional impairment by modulating miR-98-5p/EDEM1 signaling axis in neonatal mice
by: Lili Xu, et al.
Published: (2021-06-01)

The Crucial Role of Demannosylating Asparagine-Linked Glycans in ERADicating Misfolded Glycoproteins in the Endoplasmic Reticulum
by: Jianjun Zhang, et al.
Published: (2021-01-01)

Endoplasmic Reticulum (ER) Stress Response and Its Physiological Roles in Plants
by: Stephen H. Howell, et al.
Published: (2013-04-01)

Expression regulation of major histocompatibility complex (MHC) class I and class II encoding genes
by: Peter J van den Elsen, et al.
Published: (2011-10-01)

The Expression of Major Histocompatibility Class I and Major Histocompatibility Class II on Macrophages in the Presence of Aryl Hydrocarbon Antagonist (CH-223191)
by: Wilson, Caitlin Persin
Published: (2016)

Etude de la calréticuline dans les syndromes myéloprolifératifs : de la détermination de la charge allélique aux mécanismes de dégradation des variants protéiques
by: Mansier, Olivier
Published: (2017)

Tyrosinase degradation is prevented when EDEM1 lacks the intrinsically disordered region.
by: Marioara B Marin, et al.
Published: (2012-01-01)

Calnexin association with lysosomal hydrolases is limited to overexpressed enzymes destined for secretion
by: Wilson, Daniel James, 1970.
Published: (1996)

Regulation of ER stress-induced cell death by the ERK1/2 signalling pathway
by: Darling, Nicola Jane
Published: (2015)

Functional and mechanistic characterization of ubiquitin fusion degradation 1 in MYC-driven leukemogenesis
by: Huiting, Leah
Published: (2019)

Ubiquitination regulates the assembly of VLDL in HepG2 cells and is the committing step of the apoB-100 ERAD pathway[S]
by: Eric A. Fisher, et al.
Published: (2011-06-01)

The AAA-ATPase p97 facilitates degradation of apolipoprotein B by the ubiquitin-proteasome pathways⃞
by: Eric A. Fisher, et al.
Published: (2008-10-01)

Major Histocompatibility Complex and Malaria: Focus on Plasmodium vivax infection
by: Josué Costa Lima-Junior, et al.
Published: (2016-01-01)

Role of Endoplasmic Reticulum Aminopeptidases in Health and Disease: from Infection to Cancer
by: Doriana Fruci, et al.
Published: (2012-07-01)

Dexamethasone-induced selenoprotein S degradation is required for adipogenesis
by: Choon Young Kim, et al.
Published: (2013-08-01)

Chemotherapy Resistance Explained through Endoplasmic Reticulum Stress-Dependent Signaling
by: Entaz Bahar, et al.
Published: (2019-03-01)

Research advances of endoplasmic reticulum stress in high glucose environment and its related ophthalmic diseases
by: Jia-Jun Lu, et al.
Published: (2018-06-01)

Therapeutic approaches targeting endoplasmic reticulum stress in diabetic endothelial dysfunction.
Published: (2014)

The Molecular Mechanisms Underlying Mitochondria-Associated Endoplasmic Reticulum Membrane-Induced Insulin Resistance
by: Han Cheng, et al.
Published: (2020-11-01)

Fluorescent-detected retrotranslocation of an endoplasmic reticulum - associated degradation (ERAD) substrate in a mammalian in vitro system
by: Wahlman, Judit
Published: (2008)

Fluorescent-detected retrotranslocation of an endoplasmic reticulum - associated degradation (ERAD) substrate in a mammalian in vitro system
by: Wahlman, Judit
Published: (2010)

Studies on yeast protein disulphide isomerase
by: Natalia, Dessy
Published: (1994)

Regulation of endoplasmic reticulum stress by transcription factor E2F-1 in ventricular myocytes
by: Mughal, Wajihah
Published: (2012)

Regulation of endoplasmic reticulum stress by transcription factor E2F-1 in ventricular myocytes
by: Mughal, Wajihah
Published: (2012)

Toxins Utilize the Endoplasmic Reticulum-Associated Protein Degradation Pathway in Their Intoxication Process
by: Jowita Nowakowska-Gołacka, et al.
Published: (2019-03-01)